Yes, it is still possible to solo the quest as a rogue this way. I just did.

A good spot to aggro Mother Smolderweb and to hearth out afterwards was the far corner, I found.

One word of warning, though: I died once because I simply didn't notice that she had already poisoned me.
I had already come here to post a frustrated entry about how I had held out sooo long and still died unpoisoned before I thought to check my combat log, where - right before I used blinding powder, so I must have been fairly down but still in the first half of the fight - it actually said ""You are afflicted by Mother's Milk"". So there it was, and I hadn't seen it. - Quite apart from the fact that the poison shows as a bright green icon where all the poisons and spells you have on you are shown. Duh.

Anyway, in the next fight, I left my combat log on and kept a constant eye on it.

So, if you're as blind as me and tend to ignore your debuff icons, you might want to go into this fight with your combat log open, as well.

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By the way, while you're stealthing through the Spire, this quest can easily be combined with the two pet quests given by https://vanillawowdb.com/?npc=10260 Kibler: https://vanillawowdb.com/?quest=4862 En-Ay-Es-Tee-Why and https://vanillawowdb.com/?quest=4729 Kibler's Exotic Pets.

Just make sure you complete the two pet quests first - I recommend to take all your clothes and weapons off while you do, since you need to stealth around a lot and might die a few times before you have all the eggs and the Worg carrier. THEN, when you're done with those, go back to Mother Smolderweb, put your clothes and weaponry back on, wait for your Vanish to cool down and engage her.

Wow, this is a toughie! We solved it by taking turns hearthstoning OUT of the instance after being poisoned and completing the quest before being summoned back in. Our comrades continued killing spiders and worked up to the last phase of the spider section (where there were lots of eggs to be had for the returnees doing the egg quest).

The side effect of being webbed is abated when you are mounted on your ride or in flight.. I also don't recall being webbed while on board a ship (we didn't think to reset our stones to a more convenient escape point)- but it made up for that once I landed.. I think I go webbed six times in rapid succession!

I was the lowest level char in our group and had never been to BRS.. the others were impressed that I was able to noodle (or is that doodle?) a solution.

Fight well!

If you're thinking of soloing this quest at level 80 for loremaster you might want to think again. I tried a couple times just sitting there and letting her wail on me. Every time she cast the poison I resisted it. After about 50-60 casts of the spell I finally just gave up and abandoned the quest.

does the mother's milk debuff only affect those in your party, or does it affect friendly players around you?

Be warned: if you're doing this quest with other people in your group, the random web explosions can get to be VERY annoying. The snare lasts 10s and you might go close to 30s just standing around while 3 or more people's debuff procs.

For Death Knights if you don't mind going and making a sandwich it's fairly simple to use your Death Gate. It's highly unlikely that any DK has bothered to learn an anti-venom high enough to ""help"" you, and it's a direct flight. It just takes a long, long time...

Still struggling to complete this quest. I am an 80 undead rogue and I have let me hit her for a good 30 minutes. No poison yet.

For what it's worth, I am facing away from her so every attack hits me, however the poison still does not proc.

I just did this quest for Loremaster as lvl 80 Ret Pally. I had to strip down to no weapon and down to about 10k hp (which might have been 3 pieces) and just punched the spider til I got the poison. Prior to trying that I just stood there and kept resisting. Also, if you're a lvl 80 pally trying this for Loremaster or w/e make sure that you dont have your ret aura on (you could eventually kill the boss without even attacking her).

About 90 minutes into this on my rogue. In my PvE spec, so no heightened senses. I am in all my gear though, should I take everything off?

Finally got this!

Not sure if I just got 'lucky' or if this really did do it, but a user above mentioned not having heightened senses activated, so I went to my PvE spec, but I noticed 'master poisoner' had a 50% reduction of poison length. I went and just removed all of my talent points and went back to her, literally within 10 seconds of the encounter I was poisoned.

Level 80 rouge in full season 8 PvP gear.

Hope this helps another rogue!

For me, as a level 80 rogue, switching to combat spec AND taking off most of my gear finally did the trick! She poisoned me within the first 15 seconds of the encounter :D
After I killed her I stealthed out of the instance and was only webbed twice. Once you're mounted you won't get webbed anymore but you'll get the occasional ""You are mounted"" appear on your screen. Good luck everyone!

For low-level characters (Or rather, level-appropriate characters :p), you can easily complete this quest if you want to, without much inconvenience to your party. However, it takes some planning. Because you can teleport to and out of a dungeon in progress from the dungeon finder, and it returns you to your location when the run started, you can queue for LBRS and exit the dungeon when you get the debuff, if you queue at Flame's Crest. Then you can quickly turn it in and jump back into the dungeon, in less than a minute or two.

No longer available, all of Azeroth's heroes are safe from being milked by this creepy dwarf.

Be warned: this quest will make all females and tauren feel violated, or worse.